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KMID : 0368819770160040333
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Journal of the Korean Neuropsychiatr Association
1977 Volume.16 No. 4 p.333 ~ p.339
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EFFECTS OF THIOTHIXENE ON BLOOD ALCOHOL LEVEL IN RABBITS
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Abstract
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Thiothixene, which is a thioxanthene derivative, has been used in treatment of schizophrenia. The efficacy of this drug has been frequently compared to other neuroleptics, such as chlorpromazine, thioridazine and trifluoperazine. This drug has been known to cause some. extrapyramidal symptoms and hypotensive effects but these side effects
have been considered to be less marked than the extrapyramidal and hypotensive effects of most of other neuroleptics.
It. has been lately reported that chlorpromazine, lithium ion and several other psychotropic drugs elevated the blood alcohol level in rabbits.
In view of these findings, the author conducted an animal experiment to investigate the effects of thiothixene on blood alcohol level in rabbits.
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KEYWORD
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